Posts Tagged magnetic resonance
System Combines Capillary Electrophoresis And NMR Spectroscopy
By using micro-electromechanical systems (MEMS) technology, researchers at the University of Illinois have developed a chip-based analytical system that combines capillary electrophoresis and nuclear magnetic resonance (NMR) spectroscopy. Integrated microfluidic-NMR systems could have important applications in a wide variety of combinatorial chemistry areas — such as drug discovery — and might facilitate the development of desktop NMR spectrometers.
“Capillary electrophoresis and NMR spectroscopy have competing design goals, but by integrating them with MEMS technology we can maximize the performance of both systems,” said David Beebe, a professor of electrical and computer engineering and a researcher at the university’s Beckman Institute for Advanced Science and Technology. “By using very small channels and samples, we can do high-performance capillary electrophoresis separations. And by performing those separations multiple times, we can collect a large enough sample to do NMR spectroscopy.”
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MR Spectroscopy Helps Identify Cancerous Breast Tumors
Measuring the biochemical changes in breast tumors with magnetic resonance (MR) spectroscopy enables radiologists to more accurately distinguish benign tumors from cancerous ones, according to a study appearing in the August issue of the journal Radiology.
“Adding spectroscopy to breast MR examinations will not only reduce concern over possible missed cancers and unnecessary biopsy procedures, it may also improve the efficiency and quality of patient care,” said co-author Sina Meisamy, M.D., a postdoctoral fellow at the University of Minnesota Center for Magnetic Resonance Research in Minneapolis.
MR imaging of the breasts has a high rate of sensitivity (94 percent – 100 percent) for detecting tumors, but a variable rate of specificity (37 percent – 97 percent) for distinguishing malignant from benign tumors.
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Magnetic Resonance Spectroscopy and Autism Research
Autism was discovered almost a century ago, but, to this day, medical researchers do not know what causes the condition. Nevertheless, despite the fact that the cause is unknown, it is widely accepted that autism spectrum disorders are the result of brain abnormalities in relation to brain structure or function. However, due to the fact that underlying causes of these abnormalities remains a mystery, various studies have been conducted to learn more – studies such as Magnetic Resonance Spectroscopy and autism.
Magnetic resonance spectroscopy (MRS) is a scanning technique that is very similar to an MRI (magnetic resonance imaging). The main difference is the MRS method is non image based; however, both techniques can be utilized at the same time. The purpose of a magnetic resonance spectroscopy is to examine the brain’s hydrogen and phosphorus atoms, and gather information regarding the brain’s regions where chemical activity is present.
Tags: autism, autism spectrum disorder, brain, chemicals, levels, magnetic resonance, magnetic resonance imaging, magnetic resonance spectroscopy, process, research, spectroscopy, spectrum, studyRelated posts
MR Spectroscopy Significantly Reduces Need For Breast Biopsy
In a study featured in the June issue of Radiology, researchers found that imaging suspicious breast lesions with magnetic resonance (MR) spectroscopy reduced the need for biopsy by 58 percent. The investigators, from Memorial Sloan-Kettering Cancer Center in New York, discovered that with the addition of MR spectroscopy to their breast MR imaging (MRI) protocol, 23 of 40 suspicious lesions could have been spared biopsy, and none of the resultant cancers would have been missed.
“All cancers in this study were identified with MR spectroscopy. There were no false-negative results,” said Lia Bartella, M.D., lead investigator and assistant professor in the Department of Breast Imaging at Memorial Sloan-Kettering. “With the addition of MR spectroscopy to our breast MRI exam, we found that the number of biopsies recommended on the basis of MRI findings decreased significantly. These results should encourage more women to take this potentially life-saving test.”
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